Head-to-Head: What the Licences Say
| Licence record | Pro-UROL | Urolo-Q |
|---|---|---|
| Licensed use | "Helps relieve the pain of non-bacterial chronic Prostatitis. Helps relieve pain associated with chronic prostatitis to support quality of life." Also: antioxidant; supports prostate health | "Non-Bacterial Prostatitis. Helps relieve the pain of non-bacterial chronic prostatitis." |
| Dose | 1 tablet, 3 times daily (men 18+) | 1 tablet, 2 times daily (adult males) |
| Quercetin | 400 mg per tablet · 1,200 mg/day | 536.84 mg quercetin dihydrate per tablet (about 480 mg quercetin) · about 960 mg/day |
| Pollen extract | 120 mg (10:1, equivalent to 1,200 mg pollen) per tablet · 360 mg/day (3,600 mg pollen equivalent) | 44.1 mg (20:1, equivalent to 882 mg pollen) per tablet · 88.2 mg/day (1,764 mg pollen equivalent) |
| Stem bromelain | 33.33 mg per tablet · 100 mg/day | 25 mg per tablet · 50 mg/day |
| Papain | 50 mg per tablet · 150 mg/day | 50 mg per tablet · 100 mg/day |
| Other medicinal ingredient | None | Calcium carbonate 206.76 mg per tablet |
| Amounts shown on brand website | Yes | No (listed on the licence record) |
| Duration statement | None on the licence | See a practitioner if symptoms worsen or persist after 3 months |
| Licensed cautions | Ask a practitioner first if taking a blood thinner, anti-inflammatories or antibiotics; with a stomach ulcer or before surgery; with latex or fruit allergy. Do not use if allergic to bee products or pollen. | The same cautions, plus: quinolone antibiotics, kidney disease, pregnancy or breastfeeding, a 2-hour gap from other medicines, and reported headache, tingling, nausea or diarrhea. Pollen allergy is a caution rather than a do-not-use. |
What Is the Same
- The ingredients. Both contain quercetin, pollen extract, bromelain and papain.
- The evidence. Both rest on the same two ingredient trials: quercetin 500 mg twice daily for 1 month in 30 men (Shoskes 1999), and a Cernilton pollen extract for 12 weeks in 139 men with inflammatory CP/CPPS (Wagenlehner 2009). Neither product has been tested as a finished product in CP/CPPS.
- The guideline status. The 2025 AUA guideline says clinicians "may prescribe" quercetin and pollen extract (Conditional Recommendation, Grade B). That applies to the ingredients, not to either brand.
- No prescription needed.
What Is Different
Dose
Pro-UROL provides about 25% more quercetin per day than Urolo-Q (1,200 mg vs about 960 mg), and about twice the pollen equivalent. The quercetin trial used 1,000 mg a day, so both products are close to it. The pollen trial used a specific extract, Cernilton, at about 378 mg a day. Pollen extracts differ by source and processing, so neither product's pollen dose can be assumed to match the trial just by comparing milligrams. More milligrams have not been shown to mean more relief.
Warnings
Urolo-Q's licence carries more cautions. That reflects how each licence was written, not a proven difference in safety: the two products contain the same ingredients, and Pro-UROL contains more quercetin. Whichever you choose, ask your pharmacist first if you take quinolone antibiotics (such as ciprofloxacin), blood thinners or anti-inflammatories, or have kidney disease, and reassess with your doctor if you are not better after about 3 months.
Tablets and track record
Pro-UROL comes as 90 tablets (a 30-day supply at 3 a day). Urolo-Q is sold as 60 tablets (30 days at 2 a day) and has been licensed in Canada since 2013. Urolo-Q's non-medicinal ingredients include coating agents; we could not confirm from the licence whether it is time-release.
Do Bromelain and Papain Make a Difference?
Both products contain them, so this is not a point of difference. The idea that they help the body absorb quercetin is a theory. The only CP/CPPS data come from an open-label follow-up to the 1999 quercetin trial, in which 17 men took a quercetin, bromelain and papain supplement and 82% improved. That follow-up had no placebo group, so it cannot show the enzymes added benefit.
Where Q-Urol Fits
Q-Urol is a U.S. product from Farr Laboratories built on the same four ingredients. Its Canadian website, q-urol.ca, now redirects to uroloq.ca, which suggests Urolo-Q is its Canadian successor, though we found no page stating that. A U.S. product from Sunn Biolabs is also sold as "UROLO-Q"; it is a different product and we found no Canadian licence for it. If you buy online, check for NPN 80039114 on the bottle.
A placebo-controlled trial of the Q-Urol formula has been registered at the Huntsman Cancer Institute (NCT04252625), in men with radiation-related prostate symptoms after brachytherapy for prostate cancer. That is a different condition from CP/CPPS, it tested a different product from Pro-UROL, and we could not find published results.
Other Licensed Options
These two are not the only licensed choices. NOW Quercetin with Bromelain (NPN 80039849; quercetin and bromelain, no pollen) and AOR Prostate Support (NPN 80045408; pollen extract only) also carry licensed claims for the pain of non-bacterial chronic prostatitis. See which supplement ingredients have evidence.
How to Choose
- Get assessed first. Infection, BPH and other causes share these symptoms. See non-bacterial prostatitis explained.
- If you want the higher daily quercetin and pollen amounts: Pro-UROL.
- If you prefer twice-daily dosing or a longer market history: Urolo-Q.
- Either way: score your symptoms before starting (the NIH-CPSI), give it about 12 weeks, and score them again. A drop of about 6 points is a meaningful improvement. If there is none, talk to your doctor about other options such as physiotherapy, an alpha-blocker or shockwave therapy.
Read the Full Pro-UROL Evidence Review →
Health Canada LNHPD: Pro-UROL (80147704) Health Canada LNHPD: Urolo-Q (80039114)